Technical Data

017839
CAS Number
774538-96-4
Grade
Highly Purified
Molecular Formula
C35H36ClNO3S
Molecular Weight
586.18
EU Commodity Code
38220090
Shipping Temp
Blue Ice
Storage Temp
-20°C
cis-Montelukast
1-[[[(1R)-1-[3-[(1Z)-2-(7-Chloro-2-quinolinyl)ethenyl]phenyl]-3-[2-(1-hydroxy-1-methylethyl)phenyl]propyl]thio]methyl]cyclopropaneacetic Acid;

The cis geometric isomer of Montelukast. An impurity of Montelukast.

Synonyms
1-[[[(1R)-1-[3-[(1Z)-2-(7-Chloro-2-quinolinyl)ethenyl]phenyl]-3-[2-(1-hydroxy-1-methylethyl)phenyl]propyl]thio]methyl]cyclopropaneacetic Acid; Montelukast Impurity G; Montelukast EP Impurity G; Montelukast USP Related Compound G; Montelukast cis Isomer
CAS No
774538-96-4
Molecular Formula
C₃₅H₃₆ClNO₃S
Melting Point
As Reported
Solubility
Chloroform (Sligthly), Dichloromethane (Slightly), Methanol (Slightly, Sonicated)
Elemental Analysis
Theoretical: %C: 71.71, %H: 6.19, %N: 2.39
Method for Determining Identity
Proton NMR (CDCl3) Spectroscopic and Mass Spectrometric Analysis
TLC Conditions
As Reported
Storage and Stability
Light and temperature sensitive. May be stored at RT for short-term only. Long-term storage is recommended at -20°C. Store under inert atmosphere in amber vials. For maximum recovery of product, centrifuge the original vial prior to removing the cap.
Important Note
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.
Toxicity and Hazards
 All products should be handled by qualified personnel only, trained in laboratory procedures.

Intended for research use only. Not for use in human, therapeutic, or diagnostic applications.

References
1. Schoors, D., et al.: Br. J. Clin. Pharmacol., 40: 277 (1995), 2. Amin, R., et al.: J. Pharm. Biomed. Anal., 13: 155, 3. Reiss, T., et al.: J. Allergy Clin. Immunol., 98: 528 (1996)
USBio References
No references available
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