Technical Data

017915
Grade
Highly Purified
Molecular Formula
C23H25D3O12
Molecular Weight
499.48
EU Commodity Code
38220090
Shipping Temp
Blue Ice
Storage Temp
-20°C
Mycophenolic Acid-d3 β-D-Glucuronide
5-[(2E)-5-Carboxy-3-methyl-2-penten-1-yl]-1,3-dihydro-6-(methoxy-d3)-7-methyl-3-oxo-4-isobenzofuranyl β-D-Glucopyranosiduronic Acid; Mycophenolic Acid-d3 Glucosiduronate; Mycophenolic Acid-d3 Glucuronide;

A labeled metabolite of Mycophenolic Acid, an antibiotic produced by Penicillium brevi-compactum, P. Stoloniferum and related spp. A selective inhibitor of lymphocyte proliferation by blocking inosine monophosphate dehydrogenase, an enzyme involved in the de novo synthesis of purine nucleotides.

Form
Off-White Solid
Melting Point
155-159°C
Solubility
Methanol, Water

Intended for research use only. Not for use in human, therapeutic, or diagnostic applications.

References
Senda, M., et al.: Transplantation, 60, 1143 (1995), Nimmesgern, E., et al.: J. Biol. Chem., 271, 19421 (1996), Gummert, J.F., et al.: J. Pharmacol. Exp. Ther., 291, 1100 (1999),
USBio References
No references available
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