018073
CAS Number
504-96-1Grade
PurifiedMolecular Formula
C₂₀H₃₈Molecular Weight
278.52EU Commodity Code
38220090Shipping Temp
Blue IceStorage Temp
-20°CNeophytadiene
7,11,15-Trimethyl-3-methylene-1-hexadecene; 2-(4,8,12-Trimethyltridecyl)-1,3-butadiene; 2-(4,8,12-Trimethyltridecyl)buta-1,3-diene; 3-Methylene-7,11,15-trimethylhexadec-1-ene
Neophytadiene is a novel antimicrobial agent that belongs to the group of methanol-soluble oxidation catalysts. It has been shown to have a protective effect against oxidative stress, which may be due to its ability to maintain mitochondrial membrane potential and reduce reactive oxygen species production. Neophytadiene also has an anti-inflammatory effect on lipopolysaccharide-induced inflammation in vitro and in vivo studies. In addition, neophytadiene can bind with fatty acids and carotenoids, which may lead to its cardioprotective effects.
Synonyms
7,11,15-Trimethyl-3-methylene-1-hexadecene; 2-(4,8,12-Trimethyltridecyl)-1,3-butadiene; 2-(4,8,12-Trimethyltridecyl)buta-1,3-diene; 3-Methylene-7,11,15-trimethylhexadec-1-ene
Solubility
Benzene (Slightly), Chloroform (Soluble), Ethyl Acetate (Slightly), Hexanes (Sparingly)
Method for Determining Identity
Proton NMR Spectroscopic Analysis
Storage and Stability
Store at -20°C. Stable for 6 months after receipt. Hygroscopic. Under inert atmosphere. Light sensitive
Intended for research use only. Not for use in human, therapeutic, or diagnostic applications.
References
1. Rowell, C.A., et al.: J. Biol. Chem., 272, 14093 (1997),. 2. Sebti, S.M., et al.: Pharmacol. Ther., 74, 103 (1997). 3. Sun, J., et al.: Cancer Res., 59, 1919 (1999)USBio References
No references available