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018235 5-Nitro-8-hydroxyquinoline CAS: 4008-48-4

Specifications
References
CAS Number
4008-48-4
Grade
Highly Purified
Molecular Formula
C₉H₆N₂O₃
Molecular Weight
190.16
EU Commodity Code
38220090
Shipping Temp
RT
Storage Temp
4°C
5-(Hydroxyl[oxido]amino)-8-hydroxyquinoline; 5-Nitro-8-oxychinoline; 5-Nitro-8-oxyquinoline; 5-Nitro-8-quinolinol; 5-Nitrox; 5-Nitroxine; 5NOK; 8-Hydroxy-5-nitroquinoline; A 82; BAS 58; NSC 74947; NSC 74948; Nibiol; Nitroxolin; Nitroxoline; Noxibiol

5-Nitro-8-hydroxyquinoline is an antimicrobial agent used for the treatment of urinary tract infection. 5-Nitro-8-hydroxyquinoline is also a potent and reversible inhibitor of cathepsin B. 5-Nitro-8-hydroxyquinoline has been shown to have anti-cancer activity.

Synonyms
5-(Hydroxyl[oxido]amino)-8-hydroxyquinoline; 5-Nitro-8-oxychinoline; 5-Nitro-8-oxyquinoline; 5-Nitro-8-quinolinol; 5-Nitrox; 5-Nitroxine; 5NOK; 8-Hydroxy-5-nitroquinoline; A 82; BAS 58; NSC 74947; NSC 74948; Nibiol; Nitroxolin; Nitroxoline; Noxibiol
CAS Number
4008-48-4
Molecular Weight
190.16
Molecular Formula
C₉H₆N₂O₃
Melting Point
>179ºC (dec.)
Solubility
DMSO (Slightly), Methanol (Slightly, Heated)
Appearance
Supplied as a beige to very dark yellow solid.
Storage and Stability
Store at 4°C. For maximum recovery of product, centrifuge the original vial prior to removing the cap.
References
1. Mirkovic, B. et al.: ChemMedChem, 6, 1351 (2011).|2. Jiang, H. et al.: Cancer Lett., 312, 11 (2011).|3. Ghoneim, M.M. et al.: Bioelectrochemistry, 80, 162 (2011).
USBio References
No references available
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