Novobiocin Sodium Salt CAS 1476-53-5

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018601 Novobiocin Sodium Salt CAS: 1476-53-5

Specifications

References

CAS Number

1476-53-5

Grade

Highly Purified

Molecular Formula

C31H35N2NaO11

Molecular Weight

634.61

EU Commodity Code

38220090

Shipping Temp

Storage Temp

N-[7-[[3-O-(Aminocarbonyl)-6-deoxy-5-C-methyl-4-O-methyl-α-L-lyxo-hexopyranosyl]oxy]-4-hydroxy-8-methyl-2-oxo-2H-1-benzopyran-3-yl]-4-hydroxy-3-(3-methyl-2-butenyl)benzamide monosodium salt; Albamycin Sodium; Cathomycin Sodium; Cathomycin Sodium Lyovac; NSC 2382; Vulcamycin;

Novobiocin is an antibiotic that acts as an inhibitor of bacterial DNA gyrase and eukaryotic DNA topoisomerase. Studies show that Novobiocin is also an inhibitor of retrovirus RNA-dependent DNA-polymerase. Novobiocin is used in the production of positively supercoiled plasmid DNA.

References

Cozarelli, N.R.: Science, 207, 953 (1980); Sumiyoshi, Y. et al.: J. Gen. Virol., 64, 2329 (1983); Lockshon, G. et al.: Nucleic Acids Res., 11, 2999 (1983);