Technical Data

019156
CAS Number
192705-80-9
Grade
Highly Purified
Molecular Formula
C26H35Cl2N7O
Molecular Weight
532.51
EU Commodity Code
38220090
Shipping Temp
RT
Storage Temp
4°C
PD-161570
N-[6-(2,6-Dichlorophenyl)-2-[[4-(diethylamino)butyl]amino]pyrido[2,3-d]pyrimidin-7-yl]-N'-(1,1-dimethylethyl)urea; 1-Tert-butyl-3-[6-(2,6-dichloro-phenyl)-2-(4-diethylamino-butylamino)pyrido[2,3-d]pyrimidin-7-yl]urea;

A novel FGF-1 receptor tyrosine kinase inhibitor which has been shown to effectively suppress constitutive phosphorylation of the FGF-1 receptor in human ovarian carcinoma cells.

Form
Off-White Solid
Melting Point
215-230°C
Solubility
Chloroform, Methanol
Pfizer Compound

Intended for research use only. Not for use in human, therapeutic, or diagnostic applications.

References
Batley, B.L. et al.: Life Sci., 62, 143 (1997); Hamby, J.M. et al.: J. Med. Chem., 40, 2296 (1997); Nandi, S. et al.: J. Enz. Inhib. Med. Chem., 24, 937 (2009);
USBio References
No references available
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