PD-161570 CAS 192705-80-9

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019156 PD-161570 CAS: 192705-80-9

Specifications

References

CAS Number

192705-80-9

Grade

Highly Purified

Molecular Formula

C26H35Cl2N7O

Molecular Weight

532.51

EU Commodity Code

38220090

Shipping Temp

Storage Temp

4°C

N-[6-(2,6-Dichlorophenyl)-2-[[4-(diethylamino)butyl]amino]pyrido[2,3-d]pyrimidin-7-yl]-N'-(1,1-dimethylethyl)urea; 1-Tert-butyl-3-[6-(2,6-dichloro-phenyl)-2-(4-diethylamino-butylamino)pyrido[2,3-d]pyrimidin-7-yl]urea;

A novel FGF-1 receptor tyrosine kinase inhibitor which has been shown to effectively suppress constitutive phosphorylation of the FGF-1 receptor in human ovarian carcinoma cells.

Form

Off-White Solid

Melting Point

215-230°C

Solubility

Chloroform, Methanol

Pfizer Compound

References

Batley, B.L. et al.: Life Sci., 62, 143 (1997); Hamby, J.M. et al.: J. Med. Chem., 40, 2296 (1997); Nandi, S. et al.: J. Enz. Inhib. Med. Chem., 24, 937 (2009);