Technical Data

019164
CAS Number
305820-75-1
Grade
Highly Purified
Molecular Formula
C24H21Cl2N5O2
Molecular Weight
482.36
EU Commodity Code
38220090
Shipping Temp
RT
Storage Temp
4°C
PD-173952
6-(2,6-Dichlorophenyl)-8-methyl-2-[[4-(4-morpholinyl)phenyl]amino]pyrido[2,3-d]pyrimidin-7(8H)-one;

A Bcr-Abl tyrosine kinase inhibitor used in treatment research for chronic myelegenous leukemia (CML).

Form
Green Solid
Melting Point
>265°C (dec.)
Solubility
Chloroform (Sparingly), DMSO (Sparingly), Methanol (Sparingly)
Pfizer Compound

Intended for research use only. Not for use in human, therapeutic, or diagnostic applications.

References
Dorsey, J.F. et al.: Leukemia, 16, 1589 (2002); Wisniewski, D. et al.: Canc. Res., 62, 4244 (2002); Mizenina, O.A. et al.: Cell Cycle, 3, 796 (2004);
USBio References
No references available
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