Technical Data

019718
CAS Number
74150-27-9
Grade
Highly Purified
Molecular Formula
C19H18N4O2
Molecular Weight
334.37
EU Commodity Code
38220090
Shipping Temp
RT
Storage Temp
4°C
rac Pimobendan
4,5-Dihydro-6-[2-(4-methoxyphenyl)-1H-benzimidazol-6-yl]-5-methyl- 3(2H)-pyridazinone; 4,5Dihydro-6-[2-(4-methoxyphenyl)-1H-benzimidazol-5-yl]-5-methyl-3(2H)-pyridazinone; Acardi; Pimobendan;UD-CG 115; UD-CG 115BS; Vetmedin; dl-Pimobendan;

Pimobendan is a cardiotonic agent. The study of the cardiotonic mechanism of Pimobendan using ventricular muscles from rabbits and guinea pigs suggests that Pimobendan acts by inhibiting phosphodiesterase III and potassium channel. The potent venodilating action of Pimobendan makes it a suitable treatment option for patients with congestive heart failure (CHF) as it also improves systemic vasoconstriction.

Form
White Solid
Melting Point
249-251°C
Solubility
DMSO, Methanol

Intended for research use only. Not for use in human, therapeutic, or diagnostic applications.

References
Yokota, S. et al.: Yakuri Chiryo, 20, 1143 (1992); Yamamoto, M. et al.: Kank. Igaku Ken. Nenpo, 47, 155 (1996); Matsumoto, A. et al.: Cardiovas. Drugs Ther., 12, 595 (1998);
USBio References
No references available
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