rac Pimobendan

019718

CAS Number

74150-27-9

Grade

Highly Purified

Molecular Formula

C19H18N4O2

Molecular Weight

334.37

EU Commodity Code

38220090

Shipping Temp

Storage Temp

4°C

4,5-Dihydro-6-[2-(4-methoxyphenyl)-1H-benzimidazol-6-yl]-5-methyl- 3(2H)-pyridazinone; 4,5Dihydro-6-[2-(4-methoxyphenyl)-1H-benzimidazol-5-yl]-5-methyl-3(2H)-pyridazinone; Acardi; Pimobendan;UD-CG 115; UD-CG 115BS; Vetmedin; dl-Pimobendan;

Pimobendan is a cardiotonic agent. The study of the cardiotonic mechanism of Pimobendan using ventricular muscles from rabbits and guinea pigs suggests that Pimobendan acts by inhibiting phosphodiesterase III and potassium channel. The potent venodilating action of Pimobendan makes it a suitable treatment option for patients with congestive heart failure (CHF) as it also improves systemic vasoconstriction.

Form

White Solid

Melting Point

249-251°C

Solubility

DMSO, Methanol

Intended for research use only. Not for use in human, therapeutic, or diagnostic applications.

References

Yokota, S. et al.: Yakuri Chiryo, 20, 1143 (1992); Yamamoto, M. et al.: Kank. Igaku Ken. Nenpo, 47, 155 (1996); Matsumoto, A. et al.: Cardiovas. Drugs Ther., 12, 595 (1998);

USBio References

No references available

Technical Data