(3R,5S,6E)-7-[2-(Cyclopropyl-d5)-4-(4-fluorophenyl)-3-quinolinyl]-3,5-dihydroxy-6-heptenoic Acid Sodium Salt; (+)-(3R,5S,6E)-7-[2-(Cyclopropyl-d5)-4-(4-fluorophenyl)-3-quinolyl]|-3,5-dihydroxy-6-heptenoic Acid Sodium Salt; NK 104-d5 Sodium Salt
Labeled Pitavastatin. A HMG CoA reductase inhibitor. An antilipemic.
Synonyms
(3R,5S,6E)-7-[2-(Cyclopropyl-d5)-4-(4-fluorophenyl)-3-quinolinyl]-3,5-dihydroxy-6-heptenoic Acid Sodium Salt; (+)-(3R,5S,6E)-7-[2-(Cyclopropyl-d5)-4-(4-fluorophenyl)-3-quinolyl] -3,5-dihydroxy-6-heptenoic Acid Sodium Salt; NK 104-d5 Sodium Salt
CAS No
Unlabeled free acid: 147511-69-1
Molecular Formula
C₂₅H₁₈D₅FNNaO₄
Molecular Weight
448.47
Appearance
White to off-white solid
Purity
≥95%
Isotopic Purity
≥98%
MS
Conforms to reference
Melting Point
>210ºC (dec.)
Solubility
Methanol (Slightly), Water (Slightly)
Storage and Stability
Store at -20°C under inert atmosphere. For maximum recovery of product, centrifuge the original vial prior to removing the cap.
References
Yen, H., et al.: J. Clin. Invest., 98, 1253 (1996), Zou, Y., et al.: J. Biol. Chem., 274, 9760 (1999), Sun, X., et al.: Cancer Res., et al.: 61, 3382 (2001), Ladas, E.J., et al.: Clin. Oncol., 22, 517 (2004)