Prolintane CAS 493-92-5

CAS Number

493-92-5

Grade

Highly Purified

Molecular Formula

C₁₅H₂₃N

Molecular Weight

217.35

EU Commodity Code

38220090

Shipping Temp

Storage Temp

4°C

1-[1-(Phenylmethyl)butyl]pyrrolidine; 1-(1-Benzylbutyl)pyrrolidine; 1-(α-Propylphenethyl)pyrrolidine;1-Phenyl-2-pyrrolidinylpentane; Phenylpyrrolidinopentane; Prolintan; Catovit; Promotil; Villescon

Prolintane is a CNS stiumlant used as an analeptic drug. Prolintane (Catovit, Promotil, Villescon) is a stimulant[1] and norepinephrine-dopamine reuptake inhibitor developed in the 1950s. It is closely related in chemical structure to other drugs such as pyrovalerone, MDPV, and propylhexedrine and it has a similar mechanism of action.

Synonyms

1-[1-(Phenylmethyl)butyl]pyrrolidine; 1-(1-Benzylbutyl)pyrrolidine; 1-(α-Propylphenethyl)pyrrolidine;1-Phenyl-2-pyrrolidinylpentane; Phenylpyrrolidinopentane; Prolintan; Catovit; Promotil; Villescon

CAS No

493-92-5

Molecular Formula

C₁₅H₂₃N

Molecular Weight

217.35

Appearance

Colorless oil

Purity

~90%

Solubility

Chloroform, Ethyl acetate

Method for Determining Identity

Proton NMR (CDCl3) Spectroscopic and Mass Spectrometric Analysis

TLC Conditions

As Reported

Elemental Analysis

As Reported

Storage and Stability

May be stored at RT for short-term only. Long-term storage is recommended at 4°C. For maximum recovery of product, centrifuge the original vial prior to removing the cap.

References

1. Hollister, L. E.; Gillespie, H. K. (1970). "A new stimulant, prolintane hydrochloride, compared with dextroamphetamine in fatigued volunteers". The Journal of Clinical Pharmacology 10 (2): 103–109. doi:10.1177/009127007001000205. PMID 4392006. 2. GB Patent 807835 3. Nicholson, A. N.; Stone, B. M.; Jones, M. M. (1980). "Wakefullness and reduced rapid eye movement sleep: Studies with prolintane and pemoline". British Journal of Clinical Pharmacology 10 (5): 465–472. doi:10.1111/j.1365-2125.1980.tb01790.x. PMC 1430138. PMID 7437258. 4. Kyle, P. B.; Daley, W. P. (2007). "Domestic Abuse of the European Rave Drug Prolintane". Journal of Analytical Toxicology 31 (7): 415–418. doi:10.1093/jat/31.7.415. PMID 17725890. 5. Hucker, H.B. et al.: Experientia, 28, 430 (1972) 6. Hollister, L.E. et al.: J. Clin. Pharmacol. J. New Drugs, 10, 103 (1970) 7. Kuitunen, T. et al.: Meth. Find. Exp. Clin. Pharmacol., 6, 265 (1984):

USBio References

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020012 Prolintane CAS: 493-92-5

CAS Number

Grade

Molecular Formula

Molecular Weight

EU Commodity Code

Shipping Temp

Storage Temp

1-[1-(Phenylmethyl)butyl]pyrrolidine; 1-(1-Benzylbutyl)pyrrolidine; 1-(α-Propylphenethyl)pyrrolidine;1-Phenyl-2-pyrrolidinylpentane; Phenylpyrrolidinopentane; Prolintan; Catovit; Promotil; Villescon

References

USBio References

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