Technical Data

020012
CAS Number
493-92-5
Grade
Highly Purified
Molecular Formula
C₁₅H₂₃N
Molecular Weight
217.35
EU Commodity Code
38220090
Shipping Temp
RT
Storage Temp
4°C
Prolintane
1-[1-(Phenylmethyl)butyl]pyrrolidine; 1-(1-Benzylbutyl)pyrrolidine; 1-(α-Propylphenethyl)pyrrolidine;1-Phenyl-2-pyrrolidinylpentane; Phenylpyrrolidinopentane; Prolintan; Catovit; Promotil; Villescon

Prolintane is a CNS stiumlant used as an analeptic drug. Prolintane (Catovit, Promotil, Villescon) is a stimulant[1] and norepinephrine-dopamine reuptake inhibitor developed in the 1950s. It is closely related in chemical structure to other drugs such as pyrovalerone, MDPV, and propylhexedrine and it has a similar mechanism of action.

Synonyms
1-[1-(Phenylmethyl)butyl]pyrrolidine; 1-(1-Benzylbutyl)pyrrolidine; 1-(α-Propylphenethyl)pyrrolidine;1-Phenyl-2-pyrrolidinylpentane; Phenylpyrrolidinopentane; Prolintan; Catovit; Promotil; Villescon
CAS No
493-92-5
Molecular Formula
C₁₅H₂₃N
Molecular Weight
217.35
Appearance
Colorless oil
Purity
~90%
Solubility
Chloroform, Ethyl acetate
Method for Determining Identity
Proton NMR (CDCl3) Spectroscopic and Mass Spectrometric Analysis
TLC Conditions
As Reported
Elemental Analysis
As Reported
Storage and Stability
May be stored at RT for short-term only. Long-term storage is recommended at 4°C. For maximum recovery of product, centrifuge the original vial prior to removing the cap.

Intended for research use only. Not for use in human, therapeutic, or diagnostic applications.

References
1. Hollister, L. E.; Gillespie, H. K. (1970). "A new stimulant, prolintane hydrochloride, compared with dextroamphetamine in fatigued volunteers". The Journal of Clinical Pharmacology 10 (2): 103–109. doi:10.1177/009127007001000205. PMID 4392006. 2. GB Patent 807835 3. Nicholson, A. N.; Stone, B. M.; Jones, M. M. (1980). "Wakefullness and reduced rapid eye movement sleep: Studies with prolintane and pemoline". British Journal of Clinical Pharmacology 10 (5): 465–472. doi:10.1111/j.1365-2125.1980.tb01790.x. PMC 1430138. PMID 7437258. 4. Kyle, P. B.; Daley, W. P. (2007). "Domestic Abuse of the European Rave Drug Prolintane". Journal of Analytical Toxicology 31 (7): 415–418. doi:10.1093/jat/31.7.415. PMID 17725890. 5. Hucker, H.B. et al.: Experientia, 28, 430 (1972) 6. Hollister, L.E. et al.: J. Clin. Pharmacol. J. New Drugs, 10, 103 (1970) 7. Kuitunen, T. et al.: Meth. Find. Exp. Clin. Pharmacol., 6, 265 (1984):
USBio References
No references available
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