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020719 Roflumilast-d4 CAS:

Specifications
References
Grade
Highly Purified
Molecular Formula
C17H11D3Cl2F2N2O3
Molecular Weight
407.23
EU Commodity Code
38220090
Shipping Temp
Blue Ice
Storage Temp
-20°C
3-(Cyclopropyl-d4)methoxy-N-(3,5-dichloro-4-pyridinyl)-4-(difluoromethoxy)benzamide; B 9302-107-d4; BY 217-d4; BYK 20869-d4;

Labeled selective phosphodiesterase 4(PDE4) inhibitor. Antiasthmatic; in treatment of chronic obstructive pulmonary disease.

Form
White Solid
Melting Point
156-158°C
Solubility
DMSO, Methanol
References
Hatzelmann, A., et al.: J. Pharmacol. Exp. Ther., 297, 267 (2001), Schmidt, B.M.W., et al.: J. Allergy Clin. Immunol., 108, 530 (2001), Timmer, W., et al.: J. Clin. Pharmacol., 42, 297 (2002), Rabe, K.F., et al.: Lancet, 366, 563 (2005),
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