Sonepiprazole CAS 170858-33-0

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021009 Sonepiprazole CAS: 170858-33-0

Specifications

References

CAS Number

170858-33-0

Grade

Highly Purified

Molecular Formula

C21H27N3O3S

Molecular Weight

401.52

EU Commodity Code

38220090

Shipping Temp

Storage Temp

4°C

4-[4-[2-[(1S)-3,4-Dihydro-1H-2-benzopyran-1-yl]ethyl]-1-piperazinyl]benzenesulfonamide; PNU 101387; U 101387;|(S)-4-[4-[2-(3,4-Dihydro-1H-2-benzopyran-1-yl)ethyl]-1-piperazinyl]benzenesulfonamide; PF-05191680;

A selective D4 dopamine antagonist that exhibits low affinity at other monoamine receptors (Ki > 2000 nM). Induces c-fos gene expression in medial prefrontal cortex in a similar manner to Clozapine.

Form

Off-White Solid

Melting Point

183-185°C

Solubility

DMSO

Pfizer Compound

References

Merchant, K.M. et al.: J. Pharm. Exp. Ther., 279, 1392 (1996); Rubinstein, M. et al.: J. Neurosci., 21, 3756 (2001); Marona-Lewicka, D. et al.: Behav. Pharmacol., 20, 114 (2009);