Tacedinaline

021222

CAS Number

112522-64-2

Grade

Highly Purified

Molecular Formula

C15H15N3O2

Molecular Weight

269.3

EU Commodity Code

38220090

Shipping Temp

Storage Temp

4-(Acetylamino)-N-(2-aminophenyl)benzamide; Acetyldinaline; CI 994; Goe 5549; PD 123654;

Tacedinaline is a histone deacetylase (HDAC) inhibitor. Tacedinaline is an anti-cancer agent as HDAC inhibitors block angiogenesis, arrest cell growth, and lead to differentiation and apoptosis in tumor cells. Studies show Tacedinaline to be effective against acute myeloid leukemia in vitro and in vivo when used in combination with conventional anti-cancer agents.

Intended for research use only. Not for use in human, therapeutic, or diagnostic applications.

References

Pontiki, E. et al.: Med, Res. Rev., 32, 1 (2012); Hubeek, I. et al.: Oncol. Rep., 19, 1517 (2008); Pauer, L.R. et al.: Cancer Invest., 22, 886 (2004); Nemunaitis, J.J. et al.: Cancer J., 9, 58 (2003);

USBio References

No references available

Technical Data