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021302 TCS-21311 CAS: 1260181-14-3

Specifications
References
CAS Number
1260181-14-3
Grade
Highly Purified
Molecular Formula
C27H25F3N4O4
Molecular Weight
526.51
EU Commodity Code
38220090
Shipping Temp
RT
Storage Temp
RT
3-[5-[4-(2-Hydroxy-2-methyl-1-oxopropyl)-1-piperazinyl]-2-(trifluoromethyl)phenyl]-4-(1H-indol-3-yl)-1H-pyrrole-2,5-dione; TCS 21311;

A potent JAK3 inhibitor; selective for JAK3 over JAK1, JAK2 and TYK2. It also inhibits GSK-3β, PKCα and PKCθ.

References
Thoma, G. et al.: J. Med. Chem., 54, 284 (2011);
USBio References
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