Thiamphenicol CAS 15318-45-3

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021707 Thiamphenicol CAS: 15318-45-3

Specifications

References

CAS Number

15318-45-3

Grade

Highly Purified

Molecular Formula

C12H15Cl2NO5S

Molecular Weight

356.22

EU Commodity Code

38220090

Shipping Temp

Blue Ice

Storage Temp

-20°C

2,2-Dichloro-N-[(1R,2R)-2-hydroxy-1-(hydroxymethyl)-2-[4-(methylsulfonyl)phenyl]ethyl]acetamide; D-d-threo-2-Dichloroacetamido-1-(4-methylsulfonylphenyl)-1,3-|propanediol;

Thiamphenicol is an antibiotic. Thiamphenicol is the methyl-sulfonyl analogue of chloramphenicol and has a similar spectrum of activity, but is 2.5 to 5 times as potent. Thiamphenicol is used particularly for the treatment of sexually transmitted infections and pelvic inflammatory disease.

Form

White to Off-White Solid

Melting Point

165-168°C

Solubility

DMSO, Ethanol, Methanol

References

Tikhonova, E., et al.: J. Biol. Chem., 279, 32116 (2004), Baucheron, S., et al.: J. Antimicrob. Chemother., 55, 707 (2005), Pages, J., et al.: Trends. Mol. Med., 11, 382 (2005), Lomovskaya, O., et al.: Biochem. Pharmacol., 71, 910 (2006), Samosorn, S., et al.: Bioorg. Med. Chem., 14, 857 (2006),