Technical Data

022251
CAS Number
42267-27-6
Grade
Highly Purified
Molecular Formula
C9H11F3N2O4
Molecular Weight
268.19
EU Commodity Code
38220090
Shipping Temp
Blue Ice
Storage Temp
-20°C
N6-Trifluoroacetyl-L-lysine N-Carboxyanhydride
N-[4-[(4S)-2,5-Dioxo-4-oxazolidinyl]butyl]-2,2,2-trifluoroacetamide; (S)-N-[4-(2,5-Dioxo-4-oxazolidinyl)butyl]-2,2,2-trifluoroacetamide; Lys(Tfa)-NCA;

Used in the synthesis of new arborescent architectures of poly(L-lysine), called lysine dendrigraft (DGL) polymers.  DGL polymers were prepd. through a multiple-generation scheme (up to generation 5) in a weakly acidic aq. medium by polycondensing N.vepsiln.-trifluoroacetyl-L-lysine-N-carboxyanhydride (Lys(Tfa)-NCA) onto the previous generation G(n-1) of DGL, which was used as a macroinitiator.

Form
Off-White Solid
Melting Point
98-101°C
Solubility
DMSO, Ethyl Acetate

Intended for research use only. Not for use in human, therapeutic, or diagnostic applications.

References
Svenson, S., et al.: Adv. Drug Delivery Rev., 57, 2106 (2005), Shen, X., et al.: Org. Biomol. Chem., 5, 3674 (2007),
USBio References
No references available
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