(3β,5β,7β)-3,7-Dihydroxycholan-24-oic Acid; 3β,7β-Dihydroxy-5β-cholan-24-oic Acid; 3β,7β-Dihydroxy-5β-cholanic Acid; 3β,7β-Dihydroxy-5β-cholanoic Acid; Isoursodeoxycholic Acid; Ursodeoxycholic Acid EP Impurity H
Used as an anticholelithogenic
Synonyms
(3β,5β,7β)-3,7-Dihydroxycholan-24-oic Acid; 3β,7β-Dihydroxy-5β-cholan-24-oic Acid; 3β,7β-Dihydroxy-5β-cholanic Acid; 3β,7β-Dihydroxy-5β-cholanoic Acid; Isoursodeoxycholic Acid; Ursodeoxycholic Acid EP Impurity H
CAS Number
78919-26-3
Molecular Formula
C24H40O4
Molecular Weight
392.57
Purity (HPLC)
≥95%
Appearance
White to off-white solid
Solubility
Methanol (Slightly), Water (Slightly, Heated)
Melting Point
183-186°C
Method for Determining Identity
Proton NMR (CD3OD) and Mass Spectrometric Analysis
TLC Conditions
SiO2; Dichloromethane: Methanol = 9:1; Visualized with KMnO4; Single spot, Rf=0.45
Elemental Analysis
Calculated: %C: 73.43, %H: 10.27
Specific Rotation
+61.4º (c=0.4, Methanol)
Storage and Stability
May be stored at RT for short-term only. Long-term storage is recommended at 4ºC for 6 months after time of receipt.
Important Note
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.
Toxicity and Hazards
All products should be handled by qualified personnel only, trained in laboratory procedures.
References
1. Tint, G.S., et al.: Gastroenterology, 91, 1007 (1986), 2. Poupon, R.E, et al.: N. Engl. J. Med., 324, 1548 (1991)