022861
CAS Number
1232410-49-9Grade
Highly PurifiedMDL Number
MFCD19443686Molecular Formula
C₁₈H₁₆N₄O₃SMolecular Weight
368.41EU Commodity Code
38220090Shipping Temp
RTStorage Temp
RTVE 821
3-amino-6-[4-(methylsulfonyl)phenyl]-N-phenyl-2-pyrazinecarboxamide
VE 821 is a potent and selective inhibitor of DNA damage response kinase, ATR. VE 821 functions to disrupt DNA damage repair system of tumor cells, limiting their abilities for further growth.
Synonyms
3-amino-6-[4-(methylsulfonyl)phenyl]-N-phenyl-2-pyrazinecarboxamide
Molecular Formula
C₁₈H₁₆N₄O₃S
Appearance
Supplied as a yellow solid.
Solubility
Chloroform (Slightly), DMSO (Slightly)
Storage and Stability
Store at 4°C. For maximum recovery of product, centrifuge the original vial prior to removing the cap.
Intended for research use only. Not for use in human, therapeutic, or diagnostic applications.
References
1. Finlay, M., et al.: Bioorg. Medn. Chem. Letters., 22, 5352 (2012).USBio References
No references available