Ziconotide Polyacetate CAS

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022960 Ziconotide Polyacetate CAS:

Specifications

References

Grade

Highly Purified

Molecular Formula

C100H175N35O31S76 •xC2H4O2

Molecular Weight

2556.07

EU Commodity Code

38220090

Shipping Temp

Storage Temp

4°C

ω-Conotoxin M VIIA Acetate; ω-Conopeptide MVIIA Acetate; Prialt Acetate; SNX 111

Α selective antagonist of N-type voltage sensitive calcium channels (VSCC). Blocks neurotransmitter release by preventing depolarization-induced calcium influx. Used as a ligand for binding studies of voltage sensitive calcium channels. Analgesic; neuroprotective.

Form

White Solid

Melting Point

>190°C (dec.)

Solubility

Methanol

References

Olivera, B.M., et al.: Biochemistry, 26, 2086 (1987), Barksdale, C.M., et al.: J. Clin. Ligand Assay, 19, 229 (1996), McGuire, D., et al.: J. Cardiovasc. Pharmacol., 30, 400 (1997), Staats, P.S., et al.: J. Am. Med. Assoc., 291, 63 (2004),