043286
Grade
Affinity PurifiedGene ID
7223Gene #
TRPC4Accession Number
NP_001129427.1; NP_001129428.1EU Commodity Code
30021010Shipping Temp
Blue IceStorage Temp
-20°CTRPC4, CT (TRPC4, Short transient receptor potential channel 4, Trp-related protein 4)
TRPC4, Short transient receptor potential channel 4, Trp-related protein 4
Form a receptor-activated non-selective calcium permeant cation channel. Acts as a cell-cell contact-dependent endothelial calcium entry channel. Probably operated by a phosphatidylinositol second messenger system activated by receptor tyrosine kinases or G-protein coupled receptors. Mediates cation entry, with an enhanced permeability to barium over calcium. May also be activated by intracellular calcium store depletion.
Applications
Suitable for use in Western Blot, ELISA
Recommended Dilution
ELISA: 1:1,000 Western Blot: 1:100-500
Storage and Stability
May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Intended for research use only. Not for use in human, therapeutic, or diagnostic applications.
References
Mace, K.E., et al. J. Cell. Physiol. 225(2):444-453(2010)|von Spiczak, S., et al. Neuromolecular Med. 12(3):292-299(2010)|Pinheiro, A.P., et al. Am. J. Med. Genet. B Neuropsychiatr. Genet. 153B (5), 1070-1080 (2010) :|Rose, J.E., et al. Mol. Med. 16 (7-8), 247-253 (2010) :|Schaefer, M., et al. J. Biol. Chem. 277(5):3752-3759(2002)USBio References
No references available