BIX 01294 CAS 935693-62-2

CAS Number

935693-62-2

Grade

Highly Purified

Molecular Formula

C₂₈H₃₈N₆O₂

Molecular Weight

490.6

EU Commodity Code

38220090

Shipping Temp

Blue Ice

Storage Temp

4°C/-20°C

2-(Hexahydro-4-methyl-1H-1,4-diazepin-1-yl)-6,7-dimethoxy-N-4-quinazolinamine

Selective and cell permeable G9a histone lysine methyltransferase (HMTase) inhibitor. Pluripotent stem cell inducer.

Synonyms

2-(Hexahydro-4-methyl-1H-1,4-diazepin-1-yl)-6,7-dimethoxy-N-[1-(phenylmethyl)-4-piperidinyl]4-quinazolinamine

CAS No

935693-62-2

Molecular Formula

C₂₈H₃₈N₆O₂

Molecular Weight

490.6

Solubility

DMSO (5mg/ml), 100% ethanol or dimethyl formamide

Identity

Determined by MS, 1H- and 13C-NMR.

Appearance

Supplied as a white to off-white solid.

Purity

≥98% (NMR, HPLC)

Storage and Stability

Store at 4°C. Caution: Light-sensitive. For maximum recovery of product, centrifuge the original vial prior to removing the cap.

Important Note

This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.

Toxicity and Hazards

All products should be handled by qualified personnel only, trained in laboratory procedures.

References

1. Reversal of H3K9me2 by a small-molecule inhibitor for the G9a histone methyltransferase: S. Kubicek, et al.; Mol. Cell 25, 473 (2007)|2. Induction of pluripotent stem cells from mouse embryonic fibroblasts by Oct4 and Klf4 with small-molecule compounds: Y. Shi, et al.; Cell Stem Cell 3, 568 (2008)|3. Activation of pluripotency genes in human fibroblast cells by a novel mRNA based approach: J.R. Plews, et al.; PLoS One 5, e14397 (2010)

USBio References

No references available

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044611 BIX 01294 CAS: 935693-62-2

CAS Number

Grade

Molecular Formula

Molecular Weight

EU Commodity Code

Shipping Temp

Storage Temp

2-(Hexahydro-4-methyl-1H-1,4-diazepin-1-yl)-6,7-dimethoxy-N-4-quinazolinamine

References

USBio References

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