Technical Data

044996
CAS Number
732286-09-8
Grade
Highly Purified
Molecular Formula
C94H143N27O25
Molecular Weight
2051.4
EU Commodity Code
38220090
Shipping Temp
RT
Storage Temp
-20°C
Lariatin A

Peptide with lasso structure. Antimycobacterial.

CAS Number
732286-09-8
Source
Rhodococcus jostii
Molecular Weight
2051.4
Sequence
H-Gly-Ser-Gln-Leu-Val-Tyr-Arg-Glu-Trp-Val-Gly-His-Ser-Asn-Val-Ile-Lys-Pro-OH
Molecular Formula
C94H143N27O25
Solubility
Methanol or water
Appearance
Supplied as an off-white solid.
Purity
≥95% (HPLC)
Storage and Stability
Store at -20°C. For maximum recovery of product, centrifuge the original vial prior to removing the cap.
Important Note
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.
Toxicity and Hazards
 All products should be handled by qualified personnel only, trained in laboratory procedures.

Intended for research use only. Not for use in human, therapeutic, or diagnostic applications.

References
1. Lariatins, antimycobacterial peptides produced by Rhodococcus sp. K01-B0171, have a lasso structure: M. Iwatsuki, et al.; JACS 128, 7486 (2006)|2. Lariatins, novel anti-mycobacterial peptides with a lasso structure, produced by Rhodococcus jostii K01-B0171: M. Iwatsuki, et al.; J. Antibiot. (Tokyo) 60, 357 (2007)|3. Lys17 in the 'lasso' peptide lariatin A is responsible for anti-mycobacterial activity: M. Iwatsuki, et al.; Bioorg. Med. Chem. Lett. 19, 2888 (2009)|4. Molecular cloning of the gene cluster for lariatin biosynthesis of Rhodococcus jostii K01-B0171: J. Inokoshi, et al.; Appl. Microbiol. Biotechnol. 95, 451 (2012)
USBio References
No references available
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