Technical Data

045035
CAS Number
115104-28-4
Grade
Highly Purified
MDL Number
MFCD11114392
Molecular Formula
C26H26ClN2O3S2 . Na
Molecular Weight
537.1
EU Commodity Code
38220090
Shipping Temp
Blue Ice
Storage Temp
4°C/-20°C
MK-571 sodium salt

Selective leukotriene LTD4 receptor antagonist. Potent MRP1 inhibitor. Antinociceptive.

CAS Number
115103-85-0, 115104-28-4 (free base)
Molecular Weight
537.1
Molecular Formula
C26H26ClN2O3S2●Na
Solubility
Water (20mg/ml), 100% ethanol (10mg/ml), DMSO or methanol
Appearance
Supplied as a light yellow solid.
Method for Determining Identity
Proton NMR
Purity
≥97% (NMR)
Storage and Stability
Store at -20°C under inert atmosphere. Protect from light. For maximum recovery of product, centrifuge the original vial prior to removing the cap.

Intended for research use only. Not for use in human, therapeutic, or diagnostic applications.

References
1. Pharmacology of L-660,711 (MK-571): a novel potent and selective leukotriene D4 receptor antagonist: T.R. Jones, et al.; Can. J. Physiol. Pharmacol. 67, 17 (1989)|2. The leukotriene LTD4 receptor antagonist MK571 specifically modulates MRP associated multidrug resistance: V. Gekeler, et al.; BBRC 208, 345 (1995)|3. The antinociceptive effect of leukotriene D(4) receptor antagonist, MK-571, in mice: possible involvement of opioidergic mechanism: Eur. J. Pharmacol. 386, 195 (1999)
USBio References
No references available
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