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045267 SAG Analog CAS: 1401532-78-2

Specifications
References
CAS Number
1401532-78-2
Grade
Highly Purified
Molecular Formula
C28H27Cl2N3OS (trans-isomer)
Molecular Weight
524.5
EU Commodity Code
38220090
Shipping Temp
RT
Storage Temp
4°C/-20°C

Cell permeable low toxicity Sonic hedgehog (Shh) agonist. Cell permeable smoothened (Smo) agonist. Potent activator of VEGF expression in vitro.

Synonyms
Compound 10c; 3,4-Dichloro-N-(trans-4-(methylamino)cyclohexyl)-N-(3-pyridin-4-ylbenzyl)benzo[b]thiophene-2-carboxamide
CAS Number
1401532-78-2
Molecular Weight
524.5
Molecular Formula
C28H27Cl2N3OS (trans-isomer)
Solubility
DMSO
Method for Determining Identity
Proton NMR and MS
Appearance
Supplied as a white to light yellow solid.
Purity
≥98% (NMR)
Storage and Stability
For short term storage, store at 4°C. For long term, store solutions at -20°C in the dark. Stable for 1 year after receipt when stored at -20°C. Protect from light. For maximum recovery of product, centrifuge the original vial prior to removing the cap.
Purity
≥98% (NMR)
Form
Supplied as a white to light yellow solid.
Important Note
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.
References
1. Potent small molecule Hedgehog agonists induce VEGF expression in vitro: K. Seifert, et al.; Bioorg. Med. Chem. 20, 6465 (2012).
USBio References
No references available
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