TC HSD 21 (5-[(3-Bromo-4-hydroxyphenyl)methylene]-3-(4-methoxyphenyl)-2-thioxo-4-thiazolidinone)
Potent 17beta-hydroxysteroid dehydrogenase type 3 (17beta-HSD3) inhibitor (IC50 values are 6 and 40nm at human and mouse 17beta-HSD3 respectively). Displays no activity at 17beta-HSD1, 17beta-HSD2, ERalpha, androgen receptors or glucocorticoid receptors.
Storage and Stability
Lyophilized powder may be stored at -20°C. Stable for 12 months at -20°C. Reconstitute with sterile buffer or ddH2O. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Reconstituted product is stable for 6 months at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
Concentration
Not determined
Form
Supplied as a yellow solid.
Important Note
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.
