CAS 180468-38-6

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159081 (1S,3S-)Solifenacin Hydrochloride CAS: 180468-38-6

Specifications

References

CAS Number

180468-38-6

Grade

Highly Purified

Molecular Formula

C23H27ClN2O2

Molecular Weight

398.93

EU Commodity Code

38220090

Shipping Temp

Storage Temp

-20°C

(1S)-3,4-Dihydro-1-phenyl-2(1H)-isoquinolinecarboxylic Acid (3S)-1-Azabicyclo-[2.2.2]oct-3-yl Ester Hydrochloride

(1S,3S-)Solifenacin Hydrochloride is an optical isomer of Solifenacin Hydrochloride, a muscarinic M3 receptor antagoinst. Used in treatment of urinary incontinence.

Synonyms

(1S)-3,4-Dihydro-1-phenyl-2(1H)-isoquinolinecarboxylic Acid (3S)-1-Azabicyclo-[2.2.2]oct-3-yl Ester Hydrochloride

CAS No

180468-38-6

Molecular Formula

C23H27ClN2O2

Molecular Weight

398.93

Appearance

Pale yellow to yellow solid

Purity

≥96%

Melting Point

116-119ºC

Solubility

DMSO (Slightly), Methanol (Slightly)

Storage and Stability

Store at -20°C under inert atmosphere. For maximum recovery of product, centrifuge the original vial prior to removing the cap.

References

Ikeda K., et al.: Arch. Pharmacol., 366, 97, (2002), Chapple, C.R., et al.: Br. J. Urol., 93, 303 (2004), Ohtake, A., et al.: Eur. J. Pharmacol., 492, 243 (2004), Brunton, S., et al.: Curr. Med. Res. Opin., 21, 71 (2005), Habb, F., et al.: Eur. Urol. 47, 376 (2005), Payne, C.K., et al.: Drugs, 66, 175 (2006); Naito, R. et al.: J. Med. Chem., 48, 6597 (2005)