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163115 cis-2,6-Dimethylmorpholine CAS: 6485-55-8

Specifications
References
CAS Number
6485-55-8
Grade
Highly Purified
MDL Number
MFCD00078428
Molecular Formula
C₆H₁₃NO
Molecular Weight
115.07
EU Commodity Code
38220090
Shipping Temp
RT
Storage Temp
RT
(2R,6S)-rel-2,6-Dimethylmorpholine; (2R,6S)-2,6-Dimethylmorpholine; (2R,6S)-2,6-Dimethylmorpholine; 2,6-cis-Dimethylmorpholine; cis-(2R,6S)-2,6-Dimethylmorpholine; cis-2,6-Dimethylmorpholine

cis-2,6-Dimethylmorphine is used in the synthesis of p38α MAP kinase inhibitors used in the treatment of autoimmune diseases. Also used towards the synthesis of potent agonists and antagonists of 5-HT4 receptors.

Synonyms
(2R,6S)-rel-2,6-Dimethylmorpholine; (2R,6S)-2,6-Dimethylmorpholine; (2R,6S)-2,6-Dimethylmorpholine; 2,6-cis-Dimethylmorpholine; cis-(2R,6S)-2,6-Dimethylmorpholine; cis-2,6-Dimethylmorpholine
CAS No
6485-55-8
Molecular Formula
C₆H₁₃NO
Molecular Weight
115.07
Appearance
Colorless oil
Purity (GC)
≥97%
Boiling Point
147°C
Flash Point
43°C
Specific Gravity (20/20)
0.93
Refractive Index
1.45
Solubility
Chloroform (Sparingly), Dichloromethane (Sparingly), Methanol (Slightly)
Storage and Stability
May be stored at RT for short-term only. Long-term storage is recommended at -20°C. For maximum recovery of product, centrifuge the original vial prior to removing the cap.
References
Regan, J. et al.: J. Med. Chem., 46, 4676 (2003); Yang, D. et al.: J. Med. Chem., 40, 68 (1997)
USBio References
No references available
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