DOTA CAS 60239-18-1

CAS Number

60239-18-1

Grade

Highly Purified

Molecular Formula

C₁₆H₂₈N₄O₈

Molecular Weight

404.42

EU Commodity Code

38220090

Shipping Temp

Storage Temp

RT/4°C

1,4,7,10-Tetraazacyclododecane-1,4,7,10-tetraacetic Acid; 1,4,7,10-Tetra(carboxymethyl)-1,4,7,10-tetraazacyclododecane; 1,4,7,10-Tetraazacyclododecane-N,N',N'',N'''-tetraacetic acid; DOTA; NSC 681107; Tetraxetan

Bifunctional DOTA aconjugates to peptides and has become an established strategy for constructing target-specific metal containing agents including targeted MRI contrast agents and diagnostic and therapeutic radiopharmaceuticals.

Synonyms

1,4,7,10-Tetraazacyclododecane-1,4,7,10-tetraacetic Acid; 1,4,7,10-Tetra(carboxymethyl)-1,4,7,10-tetraazacyclododecane; 1,4,7,10-Tetraazacyclododecane-N,N',N'',N'''-tetraacetic acid; DOTA; NSC 681107; Tetraxetan

CAS Number

60239-18-1

Molecular Formula

C₁₆H₂₈N₄O₈

Molecular Weight

404.42

Solubility

Water (Slightly, Heated), Methanol (Slightly)

Melting Point

>225°C (dec.)

Appearance

White to Off-White Solid

Storage and Stability

Store at -20°C under inert atmosphere. For maximum recovery of product, centrifuge the original vial prior to removing the cap.

References

Lewis, M., et al.: Bioconjug. Chem., 9, 72� (1998), Chappell, L., et al.: Bioorg. Med. Chem., 7, 2313� (1999), Prantner, A., et al.: Mol. Imaging, 2, 333 (2003),� Allen, M., et al.: Chem. Biol., 11, 301 (2004), Weiner, R., et al.: BioDrugs, 19, 145 (2005), �Breeman, W., et al.: Radionuclide Peptide Cancer Therapy, 119� (2006),

USBio References

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163960 DOTA CAS: 60239-18-1

CAS Number

Grade

Molecular Formula

Molecular Weight

EU Commodity Code

Shipping Temp

Storage Temp

1,4,7,10-Tetraazacyclododecane-1,4,7,10-tetraacetic Acid; 1,4,7,10-Tetra(carboxymethyl)-1,4,7,10-tetraazacyclododecane; 1,4,7,10-Tetraazacyclododecane-N,N',N'',N'''-tetraacetic acid; DOTA; NSC 681107; Tetraxetan

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