N-Methyl Pemetrexed

165430

CAS Number

869791-42-4

Grade

Highly Purified

Molecular Formula

C₂₁H₂₃N₅O₆

Molecular Weight

441.44

EU Commodity Code

38220090

Shipping Temp

Storage Temp

4°C

N-[4-[2-(2-Amino-4,7-dihydro-1-methyl-4-oxo-1H-pyrrolo[2,3-d]pyrimidin-5-yl)ethyl]benzoyl]-L-glutamic Acid; Pemetrexed EP Impurity A

N-Methyl Pemetrexed (Pemetrexed EP Impurity A) is an impurity of Pemetrexed, an multitargeted antifolate that inhibits thymidylate synthase as well as other folate dependent enzymes

Synonyms

N-[4-[2-(2-Amino-4,7-dihydro-1-methyl-4-oxo-1H-pyrrolo[2,3-d]pyrimidin-5-yl)ethyl]benzoyl]-L-glutamic Acid; Pemetrexed EP Impurity A

CAS Number

869791-42-4

Molecular Formula

C₂₁H₂₃N₅O₆

Molecular Weight

441.44

Appearance

Off-white to pale purple solid

Purity

≥96%

Melting Point

>208°C (dec.)

Solubility

Basic Alcohol (Slightly), DMSO (Slightly), Water (Slightly, Heated)

Storage and Stability

Store at 4°C under inert atmosphere. For maximum recovery of product, centrifuge the original vial prior to removing the cap.

Intended for research use only. Not for use in human, therapeutic, or diagnostic applications.

References

Kjell, D.P., et al.: Org. Proc. Res. Develop., 9, 738 (2005);

USBio References

No references available

Technical Data

165430

CAS Number

Grade

Molecular Formula

Molecular Weight

EU Commodity Code

Shipping Temp

Storage Temp

N-Methyl Pemetrexed

N-[4-[2-(2-Amino-4,7-dihydro-1-methyl-4-oxo-1H-pyrrolo[2,3-d]pyrimidin-5-yl)ethyl]benzoyl]-L-glutamic Acid; Pemetrexed EP Impurity A

References

USBio References