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165430 N-Methyl Pemetrexed CAS: 869791-42-4

Specifications
References
CAS Number
869791-42-4
Grade
Highly Purified
Molecular Formula
C₂₁H₂₃N₅O₆
Molecular Weight
441.44
EU Commodity Code
38220090
Shipping Temp
RT
Storage Temp
4°C
N-[4-[2-(2-Amino-4,7-dihydro-1-methyl-4-oxo-1H-pyrrolo[2,3-d]pyrimidin-5-yl)ethyl]benzoyl]-L-glutamic Acid; Pemetrexed EP Impurity A

N-Methyl Pemetrexed (Pemetrexed EP Impurity A) is an impurity of Pemetrexed, an multitargeted antifolate that inhibits thymidylate synthase as well as other folate dependent enzymes

Synonyms
N-[4-[2-(2-Amino-4,7-dihydro-1-methyl-4-oxo-1H-pyrrolo[2,3-d]pyrimidin-5-yl)ethyl]benzoyl]-L-glutamic Acid; Pemetrexed EP Impurity A
CAS Number
869791-42-4
Molecular Formula
C₂₁H₂₃N₅O₆
Molecular Weight
441.44
Appearance
Off-white to pale purple solid
Purity
≥96%
Melting Point
>208°C (dec.)
Solubility
Basic Alcohol (Slightly), DMSO (Slightly), Water (Slightly, Heated)
Storage and Stability
Store at 4°C under inert atmosphere. For maximum recovery of product, centrifuge the original vial prior to removing the cap.
References
Kjell, D.P., et al.: Org. Proc. Res. Develop., 9, 738 (2005);
USBio References
No references available
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