Technical Data

165749
CAS Number
64224-21-1
Grade
Highly Purified
Molecular Formula
C8H6N2S3
Molecular Weight
226.34
EU Commodity Code
38220090
Shipping Temp
RT
Storage Temp
RT/4°C
Oltipraz
4-Methyl-5-pyrazinyl-3H-1,2-dithiole-3-thione; NSC 347901; RP 35972

Oltipraz is a synthetic, substituted 1,2-dithiole-3-thione previously used in humans as an antischistosomal agent. Animal studies have demonstrated that oltipraz is a potent inducer of Phase II detoxification enzymes, most notably glutathione-S-transferase (GST). Oltipraz is now known to be used for tumor prevention purposes.

Melting Point
176-178°C
Solubility
Chloroform, DMSo

Intended for research use only. Not for use in human, therapeutic, or diagnostic applications.

References
Yu, Z., et al.: Diabetologia., 54, 922 (2011); Benson, A.B., et al.: J. Cell. Biochem. Suppl., 17, 278 (1993);
USBio References
No references available
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