S-9-[2- CAS 14047-27-9

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166427 S-9-[2-(Hydroxypropyl] Adenine CAS: 14047-27-9

Specifications

References

CAS Number

14047-27-9

Grade

Highly Purified

Molecular Formula

C8H11N5O

Molecular Weight

193.21

EU Commodity Code

38220090

Shipping Temp

Blue Ice

Storage Temp

-20°C

(S)-9-(2-Hydroxypropyl)adenine; 9-[(2S)-2-Hydroxypropyl]adenine; L-(+)-9-(2-Hydroxypropyl)adenine; (αS)-6-Amino-α-methyl-9H-purine-9-ethanol

(S)-9-[2-(Hydroxypropyl] Adenine is an inhibitor of adenosine deaminase. (S)-9-[2-(Hydroxypropyl] Adenine is used in the preparation of antiviral acyclic nucleoside thiophosphonates such as (S)-Tenofovir Disoproxil Fumarate (T018506).

Melting Point

186-189°C

Solubility

DMSO, Methanol

References

Roux, L. et al.: Eur. J. Med. Chem., 63, 869 (2013); Schaeffer, H. et al.: J. Med. Chem., 15, 456 (1972); Schaeffer, H. & Vince, R.: J. Med. Chem., 10, 689 (1967)