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207190 Fulvic Acid CAS: 479-66-3

Specifications
References
CAS Number
479-66-3
Grade
Highly Purified
Molecular Formula
C₁₄H₁₂O₈
Molecular Weight
308.2
EU Commodity Code
38220090
Shipping Temp
Blue Ice
Storage Temp
-20°C
4,10-dihydro-3,7,8-trihydroxy-3-methyl-10-oxo-1H,3H-pyrano[4,3-b][1]benzopyran-9-carboxylic acid; 3,7,8-Trihydroxy-3-methyl-10-oxo-1,3,4,10-tetrahydropyrano[4,3-b]chromene-9-carboxylic acid

Free radical scavenger and antioxidant. Potential compound to neutralize radioactive and toxic wastes and "heal" soils. Chelates and binds scores of minerals into a bioavailable form used by cells. Shown to incorporate into bone and cartilage of rats. Antibacterial. Antifungal. beta-Hexosaminidase release inhibitor. Anti-inflammatory. Tau fibrils aggregation inhibitor (Alzheimers Disease). Antiseptic. Interrupts the dimer formation of Abeta (17-42) peptides.

Synonyms
4,10-dihydro-3,7,8-trihydroxy-3-methyl-10-oxo-1H,3H-pyrano[4,3-b][1]benzopyran-9-carboxylic acid; 3,7,8-Trihydroxy-3-methyl-10-oxo-1,3,4,10-tetrahydropyrano[4,3-b]chromene-9-carboxylic acid
CAS No
479-66-3
Molecular Formula
C₁₄H₁₂O₈
Molecular Weight
308.2
Appearance
Yellow solid
Purity
≥90% (HPLC)
Solubility
Methanol, benzene or chloroform. Insoluble in H2O.
Storage and Stability
May be stored at 4°C for short-term only. Long-term storage is recommended at -20°C. Stable for 1 year after receipt. Protect from light when in solution. For maximum recovery of product, centrifuge the original vial prior to removing the cap.
References
1. Studies in the biochemistry of micro-organisms: Fulvic acid, a new crystalline yellow pigment, a metabolic product of P. griseo-fulvum Dierckx, P. flexuosum Dale and P. Brefeldianum Dodge: A.E. Oxford, et al.; Biochem. J. 29: 1102 (1935) 2. The evidence for the incorporation of fulvic acid into the bone and cartilage of rats: C. Wang, et al. Sci. Total Environ. 19: 197 (1996). 3. An in vitro investigation of the antimicrobial activity of oxifulvic acid: C.E. J. van Rensburg, et al.; J. Antimicrob. Chemother. 46: 853 (2000). 4. Properties of fulvic acid extracted from excess sludge and its inhibiting effect on beta-hexosaminidase re- lease: H. Motojima, et al.; Biosci. Biotechnol. Biochem. 73: 2210 (2009). 5. Carbohydrate- derived fulvic acid (CHD-FA) inhibits carrageenan-induced inflammation and enhances wound healing: efficacy and toxicity study in rats: R. Sabi, et al.; Drug Dev. Res. 73: 18 (2011). 6. Fulvic acid inhibits aggregation and promotes disassembly of tau fibrils associated with Alzheimer's disease: A. Cornejo, et al.; J. Alzheim. Dis. 27: 143 (2011). 7. Carbohydrate Derived Fulvic Acid: An in vitro Investigation of a Novel Membrane Active Antiseptic Agent Against Candida albicans Biofilms: L. Sherry, et al.; Front. Microbiol. 3: 116 (2012). 8. The effect of fulvic acid on pre- and postaggregation state of Abeta (17-42): Molecular dynamics simulation studies: S. Verma, et al.; Biochim. Biophys. Acta 1834: 24 (2013)
USBio References
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