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207211 Geodin CAS: 427-63-4

Specifications
References
CAS Number
427-63-4
Grade
Highly Purified
MDL Number
MFCD00600308
Molecular Formula
C₁₇H₁₂Cl₂O₇
Molecular Weight
399.2
EU Commodity Code
38220090
Shipping Temp
RT
Storage Temp
-20°C
(1'R)-5,7-dichloro-4-hydroxy-6'-methoxy-6-methyl-3,4'-dioxo-spiro[benzofuran-2(3H),1'-[2,5]cyclohexadiene]-2'-carboxylic acid, methyl ester, Erdin (+)-form methyl ester; Estin

Plasminogen activator inhibitor (PAI-1). Glucose uptake stimulator.

Alternate Names
(1'R)-5,7-dichloro-4-hydroxy-6'-methoxy-6-methyl-3,4'-dioxo-spiro[benzofuran-2(3H),1'-[2,5]cyclohexadiene]-2'-carboxylic acid, methyl ester, Erdin (+)-form methyl ester; Estin
CAS Number
427-63-4
Source
Penicillium sp. FKI-5002
Molecular Formula
C₁₇H₁₂Cl₂O₇
Solubility
Soluble in DMSO, methanol, chloroform, acetone or ethyl acetate. Insoluble in H2O or hexane.
Molecular Weight
399.2
Appearance
Supplied as a pale yellow solid.
Purity
≥95% (HPLC)
Storage and Stability
May be stored at 4°C for short-term only. Long-term storage is recommended at -20°C. Stable for 1 year after receipt. Keep cool and dry. For maximum recovery of product, centrifuge the original vial prior to removing the cap.
Important Note
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.
Toxicity and Hazards:  All products should be handled by qualified personnel only, trained in laboratory procedures.
References
1. Enhancement of fibrinolytic activity of vascular endothelial cells by chaetoglobosin A, crinipellin B, geodin and triticone B: C. Shinohara, et al.; J. Antibiot. 53: 262 (2000). 2. Identification and preliminary SAR studies of (+)-Geodin as a glucose uptake stimulator for rat adipocytes: S. Sato, et al.; J. Antibiot. 58: 583 (2005)
USBio References
No references available
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