FFN511 (Fluorescent False Neurotransmitter 511, Vesicle Monoamine Transporter (VMAT2) Substrate, FFN511)
A fluorescent false neurotransmitter that acts as an optical tracer that inhibits serotonin binding to VMAT2-containing membranes (IC50 = 1uM). Compound has been used to assess the functional status of TH positive neurons by fluorescent measurement of uptatke and release.
Storage and Stability
Lyophilized powder may be stored at -20°C. Stable for 12 months at -20°C. Reconstitute with sterile buffer or dH2O. Aliquot to avoid repeated freezing and thawing. Store at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
Concentration
Not determined
Form
Supplied as a yellow solid.
Important Note
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.
