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217409 GYKI 52466 Hydrochloride (1-(4-Aminophenyl)-4-methyl-7,8-methylenedioxy-5H-2,3-benzodiazepine Hydrochloride, GYKI-52,466, GYK I52466) CAS: 102771-26-6

Specifications
CAS Number
102771-26-6
Grade
Highly Purified
Molecular Formula
C17H15N3O2•HCl
Molecular Weight
329.78
EU Commodity Code
38220090
Shipping Temp
Blue Ice
Storage Temp
4°C

A potent negative allosteric modulator selective for AMPA glutamate receptors (IC50 = 10-20uM) over kainate (IC50 ~450uM) and nMDA (IC50 >> 50uM) receptors. Commonly used as neuroprotectant, anticonvulsant, and skeletal muscle relaxant. Biologically viable admitted orally or systematically.

CAS Number
102771-26-6
Formula
C17H15N3O2•HCl
Primary Target
AMPA
Primary Target IC50
10-20 →M
Molar Mass
329.78
Solubility
H2O
Storage and Stability
May be stored at 4°C. For long-term storage, aliquot and store at 4°C. Do not freeze. For maximum recovery of product, centrifuge the original vial prior to removing the cap. Further dilutions can be made in assay buffer.
Purity
~98% (HPLC)
Concentration
Not determined
Form
Supplied as a yellow solid.
Important Note
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.
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