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217539 Mecamylamine Hydrochloride (N,2,3,3-Tetramethylbicyclo[2.2.1]he-ptan-2-amine hydrochloride, TC-5214, Inversine, nAChR Antagonist, Mecamylamine Hydrochloride) CAS: 826-39-1

Specifications
CAS Number
826-39-1
Grade
Highly Purified
MDL Number
MFCD00151462
Molecular Formula
C11H21N•HCl
Molecular Weight
203.76
EU Commodity Code
38220090
Shipping Temp
Blue Ice
Storage Temp
4°C

A potent, nonselective, and noncompetitive antagonist of nAChRs (IC50 = 640nM, 2.5uM, 3.6uM and 6.9uM for alpha3beta4, alpha4beta2, alpha3beta2 and alpha7 subtype nAChRs, respectively). Biologically viable admitted orally or systematically. Widely used in investigating the roles of central nAChRs in the brain functions (learning and memory, decision making, cognition) and disorders (addiction, Autisms, Tourette's syndrome, Schizophrenia and various cognitive and mood disorders).

Synonyms
N,2,3,3-Tetramethylbicyclo[2.2.1]he­ptan-2-amine hydrochloride, TC-5214, Inversine, nAChR Antagonist, Mecamylamine hydrochloride
CAS Number
826-39-1
Formula
C11H21N•HCl
Molecular Weight
203.76
Solubility
H2O
Primary Target
nAChR
Primary Target IC50
640nM
Storage and Stability
Store at 4°C. For maximum recovery of product, centrifuge the original vial prior to removing the cap.
Purity
~98% (TLC)
Concentration
Not determined
Form
Supplied as an off-white solid.
Important Note
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.
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