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239631 Merrifield Resin, 100-200 mesh (Chloromethylated Polystyrene) CAS: 55844-94-5

Specifications
CAS Number
55844-94-5
Grade
Reagent Grade
MDL Number
MFCD00146406
EU Commodity Code
38220090
Shipping Temp
RT
Storage Temp
RT
Chloromethylated polystyrene; Chloromethylated stryene/divinylbenzene copolymer; Chloromethylated styrene-divinylbenzene resin; Copolymer of styrene and divinylbenzene; chloromethylated; Poly(styrene-co-vinylbenzyl chloride-co-divinylbenzene); Polystyrene crosslinked with divinylbenzene chloromethylated

Chloromethyl polystyrene and styrene monomers are copolymerized in order to obtain the Merrifield resin. This method avoids the use of carcinogenic chloromethyl methyl ether. This resin is used in the synthesis of peptide acids using Boc strategy and can be cleaved using HF or TFMSA.

Synonyms
Chloromethylated polystyrene; Chloromethylated stryene/divinylbenzene copolymer; Chloromethylated styrene-divinylbenzene resin; Copolymer of styrene and divinylbenzene; chloromethylated; Poly(styrene-co-vinylbenzyl chloride-co-divinylbenzene); Polystyrene crosslinked with divinylbenzene chloromethylated
CAS No
55844-94-5
Appearance
Pale to yellow to white polymer beads
Infrared Spectrum
Conforms to reference
Swelling in DCM
5-9ml/g
Swelling in DMF
4-7ml/g
DVB %
1% DVB
Mesh Size
100-200
Substitution
0.8-1.5 meq/g
Loss on Drying (105±3°C, 1.5h)
≤1%
Storage and Stability
Store at RT.
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