241051
CAS Number
407-41-0Grade
Highly PurifiedMDL Number
MFCD00065935Molecular Formula
C3H8NO6PMolecular Weight
185.07EU Commodity Code
38220090UN DOT Shipping
UN3261 PGIIShipping Temp
RTStorage Temp
4°CL-O-Phosphoserine (L-Ser(H2PO3)-OH)
L-Ser(H2PO3)-OH; O-Phospho-L-serine; O-phosphono-Serine; L-Seryl phosphate; 3-O-Phosphoserine; L-Serinephosphoric acid; Serine dihydrogen phosphate ester; L-2-Amino-3-hydroxypropanoic acid 3-phosphate; L-SOP; L-Serine O-phosphate
L-O-Phosphoserine is the catalytic domain of human protein kinase C β II when complexed with a malemide inhibitor. It is also used in the purification of the Epstein-Barr virus nuclear antigen 2A. Group III mGlu agonist.
Synonyms
L-Ser(H2PO3)-OH; O-Phospho-L-serine; O-phosphono-Serine; L-Seryl phosphate; 3-O-Phosphoserine; L-Serinephosphoric acid; Serine dihydrogen phosphate ester
Molecular Formula
C3H8NO6P
Appearance
White to tan powder
Melting Point
171-174°C (lit)
Optical Rotation [[a]D20 ] (c=5 in 1M HCl)
+15.5±1.5º
Storage and Stability
Powder may be stored at 4°C. Stable for 6 months after receipt. Keep Under Inert Atmosphere Protect from light and moisture.
Important Note
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.
Toxicity and Hazards
All products should be handled by qualified personnel only, trained in laboratory procedures.
Intended for research use only. Not for use in human, therapeutic, or diagnostic applications.
References
1. A chemical biology route to site-specific authentic protein modifications. Yang et al. Science, 2016; 354:623. 2. Expanding the genetic code of Escherichia coli with phosphoserine. Park et al. Science, 2011;333:1151. 3. A phenotypic small-molecule screen identifies an orphan ligand-receptor pair that regulates neural stem cell differentiation. Saxe et al. Chem.Biol., 2007;14:1019USBio References
No references available