Bleomycin A5 Hydrochloride CAS 55658-47-4

CAS Number

55658-47-4

Grade

Highly Purified

Molecular Formula

C57H89CuN19O21S2·3HCl

Molecular Weight

1613.49

EU Commodity Code

38220090

Shipping Temp

Storage Temp

4°C

N1-[3-[(4-Aminobutyl)amino]propyl]bleomycinamide Hydrochloride

Bleomycin A5 inhibits DNA replication and repair. It also cleaves RNA in vitro and in vivo, and exhibits anticancer activity. It is used for various types of cancer such as squamous cell cancers, melanoma, sarcoma, testicular and ovarian cancer.

Synonyms

N1-[3-[(4-Aminobutyl)amino]propyl]bleomycinamide Hydrochloride

CAS No

55658-47-4 Free base: 11116-32-8

Molecular Formula

C57H89CuN19O21S2·3HCl

Molecular Weight

1613.49

Appearance

White to blue solid

Purity

≥85%

Melting Point

>185°C (dec.)

Solubility

DMSO (Slightly), Methanol (Slightly), Water (Slightly)

Storage and Stability

Store at 4°C under inert atmosphere. For maximum recovery of product, centrifuge the original vial prior to removing the cap.

Important Note

This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.

Toxicity and Hazards

All products should be handled by qualified personnel only, trained in laboratory procedures.

References

1. Zochowska, M. et al.: PLoS One, 4 (2009). 2. Zhao, J. et al.: Med. Onc., 28: 354 (2011). 3. Disney et al. (2020). Progress toward the development of the small molecule equivalent of small interfering RNA. Current Opinion in Chemical Biology, 56:63-71. 4. Truxova, et al. (2017). Rationale for the Combination of Dendritic Cell-Based Vaccination Approaches with Chemotherapy Agents. International Review of Cell And Molecular Biology, 115-156.

USBio References

No references available

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257225 Bleomycin A5 Hydrochloride (Copper complex) CAS: 55658-47-4

CAS Number

Grade

Molecular Formula

Molecular Weight

EU Commodity Code

Shipping Temp

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N1-[3-[(4-Aminobutyl)amino]propyl]bleomycinamide Hydrochloride

References

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