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259701 Artemether CAS: 71963-77-4

Specifications
References
CAS Number
71963-77-4
Grade
Highly Purified
MDL Number
MFCD28988547
Molecular Formula
C16H26O5
Molecular Weight
298.37
EU Commodity Code
38220090
Shipping Temp
Blue Ice
Storage Temp
-20°C
(3R,5aS,6R,8aS,9R,10S,12R,12aR)-Decahydro-10-methoxy-3,6,9-trimethyl-3,12-epoxy-12H-pyrano[4,3-j]-1,2-benzodioxepin; Decahydro-10-methoxy-3,6,9-trimethyl-3,12-epoxy-12H-pyrano[4,3-j]-1,2-benzodioxepin; Artemos; Artenam; Artesaph; Artesian; Dihydroartemisinin Methyl Ether; Falcidol; Gvither; Larither; Malartem; SM 224; β-Artemether; β-Dihydroartemisinin Methyl Ether

Derivative of Artemisinin. Artemether is a drug that is used to treat malaria. It is an antimalarial agent with a matrix effect, and it inhibits the polymerase chain reaction by binding to the response element of the DNA. Artemether has been shown to have long-term toxicity in animal studies and can cause adverse effects such as cardiac toxicity and drug interactions.

Synonyms
(3R,5aS,6R,8aS,9R,10S,12R,12aR)-Decahydro-10-methoxy-3,6,9-trimethyl-3,12-epoxy-12H-pyrano[4,3-j]-1,2-benzodioxepin; Decahydro-10-methoxy-3,6,9-trimethyl-3,12-epoxy-12H-pyrano[4,3-j]-1,2-benzodioxepin; Artemos; Artenam; Artesaph; Artesian; Dihydroartemisinin Methyl Ether; Falcidol; Gvither; Larither; Malartem; SM 224; β-Artemether; β-Dihydroartemisinin Methyl Ether
CAS No
71963-77-4
Molecular Formula
C16H26O5
Molecular Weight
298.37
Appearance
White crystalline powder
Purity
≥97%
Melting Point
86-88°C
Loss on Drying
≤0.5%
Solubility
Chloroform (Slightly), Methanol (Slightly)
Storage and Stability
Store at -20°C under inert atmosphere. For maximum recovery of product, centrifuge the original vial prior to removing the cap.
References
Hombhanje, F., et al.: Pharma., 3, 3581 (2010), Michael, O., et al.: Malaria J., 9, 335 (2010), Cesar, I., et al.: J. Pharm. Biomed. Anal., 54, 114 (2011)
USBio References
No references available
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