259738
CAS Number
70356-09-1Grade
Highly PurifiedMDL Number
MFCD00210252Molecular Formula
C₂₀H₂₂O₃Molecular Weight
310.39EU Commodity Code
38220090Shipping Temp
RTStorage Temp
4°CAvobenzone
1-[4-(1,1-Dimethylethyl)phenyl]-3-(4-methoxyphenyl)-1,3-propanedione; 1-(4-tert-Butylphenyl)-3-(4-methoxyphenyl)propane-1,3-dione; Butylmethoxydibenzoylmethane; Escalol 517; Eusolex 9020
Avobenzone is a sunscreen agent that absorbs ultraviolet light in the UVA range and protects the skin from sunburn. This compound is also used in other applications, such as to protect photo-sensitive devices from damage by UV radiation. Avobenzone is a derivative of coumarin with hydroxyl groups on each ring. It has been shown to be genotoxic, having the potential to induce autoimmune diseases and skin cancer in vivo. The rate of absorption of avobenzone into human skin cells varies depending on the type of cell. There are two types of avobenzone: one which absorbs UVB rays and one which absorbs UVA rays; however, it has been found that both types are able to penetrate into the deeper layers of skin cells. This may lead to harmful effects, including DNA damage or cancerous changes in cells.
Synonyms
1-[4-(1,1-Dimethylethyl)phenyl]-3-(4-methoxyphenyl)-1,3-propanedione; 1-(4-tert-Butylphenyl)-3-(4-methoxyphenyl)propane-1,3-dione; Butylmethoxydibenzoylmethane; Escalol 517; Eusolex 9020
Molecular Formula
C₂₀H₂₂O₃
Appearance
White to off-white to yellow powder
1HMR Spectrum
Conforms to reference
Combustion Residue
As Reported
Storage and Stability
Store at 4°C. Stable for 6 months after receipt.
Important Note
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.
Toxicity and Hazards
All products should be handled by qualified personnel only, trained in laboratory procedures.
Intended for research use only. Not for use in human, therapeutic, or diagnostic applications.
References
1. Leal, L., et al.: Environ. Sci. Technol., 44, 6835 (2010). 2. Gohil, V., et al.: Nat. Biotechnol., 28, 249 (2010). 3. Chem. and Eng. News page 22, Aug. 6 (2018)USBio References
No references available