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271302 Deflazacort CAS: 14484-47-0

Specifications
References
CAS Number
14484-47-0
Grade
Highly Purified
MDL Number
MFCD00866106
Molecular Formula
C₂₅H₃₁NO₆
Molecular Weight
441.52
EU Commodity Code
38220090
Shipping Temp
RT
Storage Temp
4°C
(11β,16β)-21-(Acetyloxy)-11-hydroxy-2'-methyl-5'H-pregna-1,4-dieno[17,16-d]oxazole-3,20-dione; Azacort; Azacortinol; Calcort; DL 458IT; Deflan; Deflazacort; Dezacor; Dezacort; Flantadin; L 5458; Lantadin; MDL 458; Oxazacort; 2-((6aR,6bS,7S,8aS,8bS,11aR,12aS,12bS)-7-hydroxy-6a,8a,10-trimethyl-4-oxo-1,2,4,6a,6b,7,8,8a,11a,12,12a,12b-dodecahydro-8bH-naphtho[2',1':4,5]indeno[1,2-d]oxazol-8b-yl)-2-oxoethyl acetate

A systemic corticosteroid. A derivative of prednisolone. Used for rheumatoid arthritis and lupus.

Synonyms
(11β,16β)-21-(Acetyloxy)-11-hydroxy-2'-methyl-5'H-pregna-1,4-dieno[17,16-d]oxazole-3,20-dione; Azacort; Azacortinol; Calcort; DL 458IT; Deflan; Deflazacort; Dezacor; Dezacort; Flantadin; L 5458; Lantadin; MDL 458; Oxazacort; 2-((6aR,6bS,7S,8aS,8bS,11aR,12aS,12bS)-7-hydroxy-6a,8a,10-trimethyl-4-oxo-1,2,4,6a,6b,7,8,8a,11a,12,12a,12b-dodecahydro-8bH-naphtho[2',1':4,5]indeno[1,2-d]oxazol-8b-yl)-2-oxoethyl acetate
CAS No
14484-47-0
Molecular Formula
C₂₅H₃₁NO₆
Molecular Weight
441.52
Appearance
White to off-white powder
Purity
≥98%
Melting Point
>215°C (dec.)
Solubility
Chloroform (Slightly), Methanol (Slightly)
Storage and Stability
May be stored at RT for short-term only. Long-term storage is recommended at -20°C. For maximum recovery of product, centrifuge the original vial prior to removing the cap.
References
Nathansohn, G., et al.: J. Med. Chem., 10,799 (1967), Schiatti, P., et al.: Arzneim. Forsch., 30, 1543 (1980), Cavall-Perin, P., et al.: Eur. J. Clin. Pharmacol., 26, 357 (1984), Imbimbo, B., et al.: Adv. Exp. Med. Biol., 171, 241 (1984)
USBio References
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