Technical Data

278358
CAS Number
126-07-8
Grade
Highly Purified
Molecular Formula
C₁₇H₁₇ClO₆
Molecular Weight
352.77
EU Commodity Code
38220090
Shipping Temp
RT
Storage Temp
4°C
Griseofulvin (Amudane, Fulcin)
(1'S,6'R)-7-Chloro-2',4,6-trimethoxy-6'-methyl-spiro[benzofuran-2(3H),1'-[2]cyclohexene]-3,4'-dione; Amudane; Fulcin; Grisovi; (+)-Griseofulvin; Spirofulvin; Sporostatin; Xuanjing; (2S)-trans-7-Chloro-2',4,6-trimethoxy-6'-methylspiro(benzofuran-2[3H],1'-[2]cyclohexene)-3,4'-dione

Antifungal drug used both in animal and in humans, to treat rigworm infections of the skin and nails. It is derived from the mold Penicillium griseofulvum.

Environmental contaminants; Food contaminants.
Synonyms
(1'S,6'R)-7-Chloro-2',4,6-trimethoxy-6'-methyl-spiro[benzofuran-2(3H),1'-[2]cyclohexene]-3,4'-dione; Amudane; Fulcin; Grisovi; (+)-Griseofulvin; Spirofulvin; Sporostatin; Xuanjing; (2S)-trans-7-Chloro-2',4,6-trimethoxy-6'-methylspiro(benzofuran-2[3H],1'-[2]cyclohexene)-3,4'-dione
CAS No
126-07-8
Molecular Formula
C₁₇H₁₇ClO₆
Molecular Weight
352.77
Appearance
White to off-white solid
Purity
≥97% (HPLC)
1H-NMR Spectrum
Conforms to reference
Melting Point
218-220°C
Loss on Drying
1%
Solubility
Chloroform (Slightly, Sonicated), Ethyl Acetate (Slightly)
Storage and Stability
May be stored at RT for short-term only. Long-term storage is recommended at 4°C. For maximum recovery of product, centrifuge the original vial prior to removing the cap.

Intended for research use only. Not for use in human, therapeutic, or diagnostic applications.

References
Oxford, et al., Biochem. J., 33, 240 (1939); Townley, E.R., et al., Anal. Profiles Drug Subs., 8, 219 (1979)
USBio References
No references available
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