Technical Data

281697
CAS Number
30685-43-9
Grade
Highly Purified
Molecular Formula
C42H66O14
Molecular Weight
794.97
EU Commodity Code
38220090
Shipping Temp
RT
Storage Temp
4°C
b-Methyldigoxin
(3β,5β,12β)-3-[(O-2,6-Dideoxy-4-O-methyl-β-D-ribo-hexopyranosyl-(14)-O-2,6-dideoxy-β-D-ribo-hexopyranosyl-(14)-2,6-dideoxy-β-D-ribo-hexopyranosyl)oxy]-12,14-dihydroxycard-20(22)-enolide; 4’’’-Methyldigoxin; 4’’’-O-Methyldigoxin; Lanirapid; Lanitop; Medigoxin; Methyldigoxin; Metildigoxin

Cardiotonic. Obtained by the O-methylation of Digoxin.

Synonyms
(3β,5β,12β)-3-[(O-2,6-Dideoxy-4-O-methyl-β-D-ribo-hexopyranosyl-(14)-O-2,6-dideoxy-β-D-ribo-hexopyranosyl-(14)-2,6-dideoxy-β-D-ribo-hexopyranosyl)oxy]-12,14-dihydroxycard-20(22)-enolide; 4’’’-Methyldigoxin; 4’’’-O-Methyldigoxin; Lanirapid; Lanitop; Medigoxin; Methyldigoxin; Metildigoxin
CAS Number
30685-43-9
Molecular Formula
C42H66O14
Purity
≥96%
Appearance
White to off-white solid
Melting Point
220-223ºC
Solubility
DMSO (Slightly), Methanol (Slightly)
Specific Optical Rotation [α]Hg 546
+22.0 to +25.5°
Method for Determining Identity
Proton NMR (DMSO-d6) Spectroscopic and Mass Spectrometric analysis
TLC Conditions
SiO2; Dichloromethane: Methanol=9:1; Visualized with (UV 280NM) and AMCS; Rf=0.50
Atmosphere
Inert Gas
Storage and Stability
May be stored at RT for short-term only. Long-term storage is recommended at 4°C. Stable for 6 months after receipt. For maximum recovery of product, centrifuge the original vial prior to removing the cap. Hygroscopic. Store under inert atmosphere.
Important Note
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.
Toxicity and Hazards
 All products should be handled by qualified personnel only, trained in laboratory procedures.

Intended for research use only. Not for use in human, therapeutic, or diagnostic applications.

References
1. Hunter, J., et al.: J. Biol. Chem., 268, 14991 (1993), 2. Greiner, B., et al.: J. Clin. Invest., 104, 147 (1999). 3. Jun, A., et al.: J. Pharm.Pharm. Sci., 4, 263 (2001). 4. Sugiyama, D., et al.: Drug Metab. Dispos., 30, 220 (2002)
USBio References
No references available
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