Propyl Paraben (4-Hydroxybenzoate)
4-Hydroxybenzoic Acid Propyl Ester; 4-Hydroxybenzoic Acid Propyl Ester; Aseptoform P; Bonomold OP; Chemocide PK; Mekkings P; NSC 23515; Propyl Chemosept; Propyl p-Hydroxybenzoate; Propylparasept; n-Propylparaben
N-Propyl-4-hydroxybenzoate (NPHB) is a preservative that belongs to the class of glycol ethers. It is used in pharmaceuticals and cosmetics as an anti-microbial agent. NPHB is effective against Gram positive bacteria and fungi, but not against Gram negative bacteria such as Pseudomonas aeruginosa. NPHB is also used as an analytical reagent for the determination of p-hydroxybenzoic acid (pHBA) in drugs and other products. The matrix effect can be eliminated by using a mixture of methanol and water as the solvent. It has been shown that cancer tissues have higher enzyme activities than normal tissues, which may result in increased sensitivity to this compound.
Synonyms
4-Hydroxybenzoic Acid Propyl Ester; 4-Hydroxybenzoic Acid Propyl Ester; Aseptoform P; Bonomold OP; Chemocide PK; Mekkings P; NSC 23515; Propyl Chemosept; Propyl p-Hydroxybenzoate; Propylparasept; n-Propylparaben
Molecular Formula
C₁₀H₁₂O₃
Appearance
White to off-white powder
Solubility
DMSO (Slightly), Methanol (Slightly)
Storage and Stability
May be stored at RT for short-term only. Long-term storage is recommended at 4°C. For maximum recovery of product, centrifuge the original vial prior to removing the cap.
Important Note
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.
Toxicity and Hazards
All products should be handled by qualified personnel only, trained in laboratory procedures.
