Technical Data

288412
CAS Number
110429-35-1
Grade
Highly Purified
MDL Number
MFCD03658863
Molecular Formula
C₁₉H₂₀FNO₃·HCl
Molecular Weight
374.84
EU Commodity Code
38220090
Shipping Temp
RT
Storage Temp
RT
Paroxetine Hydrochloride Hemihydrate
(3S,4R)-(-)-3-[(1,3-Benzodioxol-5-yloxy)methyl]-4-(4-fluorophenyl)piperidine Hydrochloride Hemihydrate

A very potent uptake inhibitor highly selective for 5-HT transporter (Ki = 0.065nM and 0.05nM for human and rat 5-HT transporters, respectively). A popular antidepressant drug of the SSRI type. Used to treat major depression, obsessive-compulsive disorder, panic disorder, social anxiety, posttraumatic stress disorder, generalized anxiety disorder and vasomotor symptoms.

Synonyms
(3S,4R)-(-)-3-[(1,3-Benzodioxol-5-yloxy)methyl]-4-(4-fluorophenyl)piperidine Hydrochloride Hemihydrate
CAS No
110429-35-1
Molecular Formula
C₁₉H₂₀FNO₃·HCl
Molecular Weight
374.84
Purity
≥98% (HPLC) 
Appearance
White to Light yellow powder
Solubility
Ethanol
Specific Rotation [a]20/D ((C=1, MeOH, anhy)
-88.0 to -92.0º
Water
2-3%
Melting Point
142°C (dec.) (lit)
Primary Target
5-HT Uptake Transporter
Primary Target Ki
0.065nM
Storage and Stability
Store at RT. Stable for 12 months after receipt.
Important Note
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.
Toxicity and Hazards
 All products should be handled by qualified personnel only, trained in laboratory procedures.

Intended for research use only. Not for use in human, therapeutic, or diagnostic applications.

References
No references available
USBio References
No references available
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