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289077 Spironolactone CAS: 52-01-7

Specifications
References
CAS Number
52-01-7
Grade
Highly Purified
Molecular Formula
C₂₄H₃₂O₄S
Molecular Weight
416.57
EU Commodity Code
38220090
Shipping Temp
RT
Storage Temp
4°C
7α,7α)-7-(Acetylthyo)-17-hydroxy-3-oxopregn-4-one-21-carboxylic Acid γ-Lactone; |7α-Acetylthio-3-oxo-17α-pregn-4-ene-21,17-carbolactone; SC-9420; Adactone

Spironolactone is a synthetic 17-lactone steroid which is a renal competitive aldosterone antagonist in a class of pharmaceuticals called potassium-sparing diuretics, used primarily to treat ascites in patients with liver disease, low-renin hypertension, hypokalemia, and Conn’s syndrome.

Synonyms
7α,7α)-7-(Acetylthyo)-17-hydroxy-3-oxopregn-4-one-21-carboxylic Acid γ-Lactone; 7α-Acetylthio-3-oxo-17α-pregn-4-ene-21,17-carbolactone; SC-9420; Adactone
CAS Number
52-01-7
Molecular Formula
C₂₄H₃₂O₄S
Molecular Weight
416.57
Appearance
White to Pale Beige Solid
Purity
≥90%
Melting Point
204-206ºC
Solubility
Chloroform (Slightly), Methanol (Slightly, Heated)
Storage
Refrigerator, 4°C
References
Sutter, J.L., et al.: Anal. Profiles Drug Subs., 4, 431 (1975)
USBio References
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